Association of tyrosine hydroxylase 01 (TH01) microsatellite and insulin gene (INS) variable number of tandem repeat (VNTR) with type 2 diabetes and fasting insulin secretion in Mexican population.
Jaime Berumen-CamposLorena Orozco-OrozcoHéctor Gallardo-RincónE Juárez-TorresE BarreraMiguel Cruz-LópezR E BenutoEspiridión Ramos-MartínezM Marin-MadinaA Alvarado-SilvaA Valladares-SalgadoJesús Peralta-RomeroHumberto Garcia-OrtizLuis-Alberto Martínez-JuárezA MontoyaSandra-Georgina Solano-GálvezJesus AlegrePablo Kuri-MoralesRoberto Tapia-ConyerPublished in: Journal of endocrinological investigation (2023)
Larger TH01 alleles and rs689 A allele may potentiate insulin synthesis in males without T2D, a process disabled in those with T2D.