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Association of tyrosine hydroxylase 01 (TH01) microsatellite and insulin gene (INS) variable number of tandem repeat (VNTR) with type 2 diabetes and fasting insulin secretion in Mexican population.

Jaime Berumen-CamposLorena Orozco-OrozcoHéctor Gallardo-RincónE Juárez-TorresE BarreraMiguel Cruz-LópezR E BenutoEspiridión Ramos-MartínezM Marin-MadinaA Alvarado-SilvaA Valladares-SalgadoJesús Peralta-RomeroHumberto Garcia-OrtizLuis-Alberto Martínez-JuárezA MontoyaSandra-Georgina Solano-GálvezJesus AlegrePablo Kuri-MoralesRoberto Tapia-Conyer
Published in: Journal of endocrinological investigation (2023)
Larger TH01 alleles and rs689 A allele may potentiate insulin synthesis in males without T2D, a process disabled in those with T2D.
Keyphrases
  • type diabetes
  • glycemic control
  • blood glucose
  • insulin resistance
  • genome wide
  • copy number
  • dna methylation
  • blood pressure
  • metabolic syndrome
  • skeletal muscle
  • weight loss