Tandem mass spectrometric analysis of novel caffeine scaffold-based bifunctional compounds for Parkinson's disease.
Chukwunonso K NwabufoAnas El-AneedEd S KrolPublished in: Rapid communications in mass spectrometry : RCM (2020)
The collision-induced tandem mass spectrometry (CID-MS/MS) analysis of these novel bifunctional compounds revealed compound-specific diagnostic product ions and neutral losses for all three tested bifunctional compounds. The established MS/MS fingerprint will be applied to the future development of qualitative and quantitative methods.
Keyphrases
- ms ms
- tandem mass spectrometry
- ultra high performance liquid chromatography
- high performance liquid chromatography
- liquid chromatography
- simultaneous determination
- gas chromatography
- highly efficient
- high resolution
- liquid chromatography tandem mass spectrometry
- metal organic framework
- mass spectrometry
- solid phase extraction
- high glucose
- diabetic rats
- single cell
- oxidative stress
- current status
- endothelial cells
- tissue engineering