An evaluation of the completeness of drug-drug interaction-related information in package inserts.
Giok Qin NgGrant Edward SklarHui Ting ChngPublished in: European journal of clinical pharmacology (2016)
The completeness score of DDI-related information in the PIs varied extensively amongst and within drug classes. A consensus between the authorities and drug companies on the type and quality of DDI-related information to be included could improve their completeness in PIs and make PIs a valuable source of DDI reference. Decision trees, albeit not validated yet, lay the groundwork for a valuable tool to evaluate DDI-related or other drug information.