Sequence matters: Total body irradiation (TBI)-based myeloablative conditioning with post-transplant cyclophosphamide may reduce the early nonrelapse mortality compared with pretransplant cyclophosphamide plus TBI.
Sara RedondoGarcía-Cadenas IreneAntonio VilaAlbert EsquirolJ M PortosSilvana NovelliSilvana SaavedraCarol MorenoAna GarridoMiguel Arguello-TomasGuadalupe OñateJordi López-PardoAna-Carolina CaballeroSara MiqueleizJavier BrionesJorge SierraGemma SanchoRodrigo MartinoPublished in: European journal of haematology (2023)
The study confirms the safety and efficacy of a novel FluTBI-PTCy platform with reduced incidence of severe acute and chronic GVHD, and early improvement of NRM.