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The Safety and Efficacy of Intra-Arterial versus Intravenous Neoadjuvant Chemotherapy in Patients with Locally Advanced Cervical Cancer: A Meta-Analysis.

Cheng LiuRan CuiMiaomiao LiYing FengHuimin BaiZhenyu Zhang
Published in: Evidence-based complementary and alternative medicine : eCAM (2020)
Platinum-based neoadjuvant chemotherapy was well tolerated in patients with locally advanced cervical cancer and showed moderate response activity. Compared to intravenous neoadjuvant chemotherapy, intra-arterial neoadjuvant chemotherapy had an evident advantage in terms of the clinical response while maintaining a similar toxicity rate. The clinical efficacy of intra-arterial neoadjuvant chemotherapy deserves further evaluation.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • rectal cancer
  • squamous cell carcinoma
  • lymph node
  • sentinel lymph node
  • radiation therapy
  • phase ii study
  • high dose
  • high intensity
  • early stage