High turnover of types III and VI collagen in progressive idiopathic pulmonary fibrosis.
Nils HoyerHenrik JessenThomas S PriorJannie Marie Bülow SandDiana J LeemingMorten A KarsdalEmilia K A ÅttingsbergGustav K M VangsgaardElisabeth BendstrupSaher B ShakerPublished in: Respirology (Carlton, Vic.) (2021)
Blood biomarkers of types III and VI collagen turnover, assessed at the time of diagnosis, are associated with several indices of disease severity, short-term progression and long-term mortality. These biomarkers can help to identify patients with a high ECM remodelling phenotype at high risk of disease progression and death.