Once-daily fluticasone furoate/vilanterol combination versus twice-daily budesonide/formoterol combination in the treatment of controlled stable asthma: a randomized crossover trial.
Kazuki FuruhashiTomoyuki FujisawaDai HashimotoYousuke KamiyaHideki YasuiMasato KarayamaYuzo SuzukiHironao HozumiNoriyuki EnomotoYutaro NakamuraNaoki InuiTakafumi SudaPublished in: Journal of asthma and allergy (2019)
The present study indicates that once-daily FF/VI DPI is not inferior to twice-daily BUD/FM DPI in clinical effect and more likely to improve inconvenience and forgetfulness in inhalation adherence barriers for stable asthma control therapy. Once-daily FF/VI DPI may be an effective alternative for asthma maintenance treatment.