Prevention of intrauterine fetal growth restriction by administrating C1q/TNF-related protein 6, a specific inhibitor of the alternative complement pathway.

Mayu KurokawaAi TakeshitaShu HashimotoMasayasu KoyamaYoshiharu MorimotoDaisuke Tachibana

Published in: Journal of assisted reproduction and genetics (2022)

Taken together, the supplementation with a protein that regulates the alternative complement pathway in vivo improves FGR and promotes spiral artery remodeling in a mouse model of miscarriage and FGR.

Keyphrases

mouse model
rheumatoid arthritis
protein protein
binding protein
small molecule