Repeated Glucose Deprivation/Reperfusion Induced PC-12 Cell Death through the Involvement of FOXO Transcription Factor.
Na HanYou Jeong KimSu Min ParkSeung Man KimJi Suk LeeHye Sook JungEun Ju LeeTae Kyoon KimTae Nyun KimMin Jeong KwonSoon Hee LeeMi-Kyung KimByoung Doo RheeJeong Hyun ParkPublished in: Diabetes & metabolism journal (2016)
Repeated glucose deprivation/reperfusion caused the neuronal cell death. Activated FOXO3 via the PI3K/Akt pathway in repeated glucose deprivation/reperfusion was involved in genes related to apoptosis.
Keyphrases
- cell death
- cerebral ischemia
- transcription factor
- cell cycle arrest
- acute myocardial infarction
- blood glucose
- acute ischemic stroke
- subarachnoid hemorrhage
- pi k akt
- brain injury
- blood brain barrier
- signaling pathway
- genome wide identification
- oxidative stress
- high glucose
- genome wide
- endoplasmic reticulum stress
- heart failure
- dna binding
- drug induced
- percutaneous coronary intervention
- diabetic rats
- coronary artery disease
- metabolic syndrome
- endothelial cells
- adipose tissue
- acute coronary syndrome
- bioinformatics analysis