Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis.
Nicholas Alexander KennedyB WarnerE L JohnstonL FlandersP HendyN S DingR HarrisA S FadraC BasquillC A LambF L CameronC D MurrayM ParkesI GoodingT AhmadD R GayaS MannJ O LindsayJ GordonJ SatsangiA HartS McCartneyP Irvingnull nullC W LeesPublished in: Alimentary pharmacology & therapeutics (2016)
Assimilation of all available data reveals remarkable homogeneity. Approximately one-third of patients with IBD flare within 12 months of withdrawal of anti-TNF therapy for sustained remission.