Persistent Apoptotic Enteropathy in an Individual With Marginal Cell Lymphoma.
Kyle YuquimpoPiyush NathaniHarsh PatelAndrea DecinoFortune UnegbuAmeer HamzaPublished in: ACG case reports journal (2023)
Apoptotic enteropathy is a histological finding of increased crypt apoptosis that is commonly associated with diarrhea. Several etiologies for this disease state including immunodeficiency, autoimmune, infection, hereditary, checkpoint inhibitors, immunosuppressants, and immunomodulators have been previously described. We describe an extremely rare case of a patient with marginal cell lymphoma treated with bendamustine, rituximab, and obinutuzumab presenting with severe, relapsing, chronic diarrhea with persistent apoptotic enteropathy of unknown etiology, despite hematological remission and discontinuation of treatment for 1 year.
Keyphrases
- cell death
- rare case
- diffuse large b cell lymphoma
- multiple sclerosis
- single cell
- anti inflammatory
- cell therapy
- case report
- cell cycle arrest
- chronic lymphocytic leukemia
- oxidative stress
- disease activity
- irritable bowel syndrome
- rheumatoid arthritis
- early onset
- signaling pathway
- mesenchymal stem cells
- replacement therapy
- smoking cessation
- ulcerative colitis