COVID-19 Recovery: Consistent Absence of Cerebrospinal Fluid Biomarker Abnormalities in Patients With Neurocognitive Post-COVID Complications.

Nelly KanbergAnna GrahnErika StentoftDaniel BremellAylin YilmazMarie StudahlStaffan NilssonMichael SchöllJohanna M GostnerKaj BlennowHenrik ZetterbergNikhil PadmanabhanRachel CohenSalvia MisaghianDaniel RomeroChristopher CampbellAnu MathewMingyue WangGeorge B SigalMartin StengelinArvid EdénMagnus Gisslén

Published in: The Journal of infectious diseases (2023)

We found no evidence of ongoing viral replication, immune activation, or CNS injury in plasma or CSF in patients with neurocognitive PCC compared with COVID-19 controls or healthy volunteers, suggesting that neurocognitive PCC is a consequence of events suffered during acute COVID-19 rather than persistent viral CNS infection or residual CNS inflammation.

Keyphrases

sars cov
coronavirus disease
cerebrospinal fluid
respiratory syndrome coronavirus
blood brain barrier
bipolar disorder
oxidative stress
liver failure
hepatitis b virus