ChREBP-regulated lipogenesis is not required for the thermogenesis of brown adipose tissue.
Chun-Chun WeiPing WangQi DongXian-Hua MaMing LuShasha QiJian-Hui ShiZhifang XieAn-Jing RenWeiping J ZhangPublished in: International journal of obesity (2005) (2022)
Our work indicates that ChREBP regulates de novo lipogenesis in BAT and glucose tolerance, but is not required for non-shivering thermogenesis by BAT under acute or long-term cold exposure.