A new approach for seasonal pattern: is it related to bipolarity dimension? Findings from an Italian multicenter study.
Andrea AgugliaAlessandro CuomoAndrea AmerioSimone BolognesiGabriele Di SalvoLaura Fusar-PoliArianna GoracciTeresa SuraceGianluca SerafiniEugenio AgugliaMario AmoreAndrea FagioliniGiuseppe MainaPublished in: International journal of psychiatry in clinical practice (2021)
A large number of patients with BD and seasonal pattern, but also a considerable number of patients with MDD and seasonal pattern, endorsed manic items during a current MDE. Seasonal pattern should be associated with a concept of bipolarity in mood disorders and not only related to bipolar disorder. A correct identification of seasonal patterns may lead to the implementation of personalised pharmacological treatment approaches.KEY POINTSHigh prevalence of mixed features in mood disorders with seasonal pattern, supporting the need for a dimensional approach to major depressive disorder and bipolar disorder.Significant percentage of patients with a primary diagnosis of major depressive disorder had seasonal pattern.Significant percentage of patients with a primary diagnosis of major depressive disorder reported (hypo)manic symptomatology.