Occupational exposure to pesticides is associated with differential DNA methylation.

Diana A van der Plaat Kim de Jong Maaike M De Vries Cleo C van Diemen Ivana Nedeljković Hans J Kromhoutnull nullRoel C H Vermeulen Dirkje S Postma Cornelia M Van Duijn H Marike Boezen Judith E Vonk

Published in: Occupational and environmental medicine (2018)

We show for the first time that occupational exposure to pesticides is genome-wide associated with differential DNA methylation. Further research should reveal whether this differential methylation plays a role in the airway disease pathogenesis induced by pesticides.

Keyphrases

genome wide
dna methylation
risk assessment
gene expression
gas chromatography
copy number
mass spectrometry
high resolution
solid phase extraction