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Skin regeneration is accelerated by a lower dose of multipotent mesenchymal stromal/stem cells-a paradigm change.

Gertraud EylertReinhard DolpAlexandra ParousisRichard ChengChristopher AugerMagdalena HolterIngrid Lang-OlipViola ReinerLars-Peter KamolzMarc G Jeschke
Published in: Stem cell research & therapy (2021)
This regenerative cell therapy study using MSCs shows efficacy toward a low dose, which changes the paradigm that more cells lead to better wound healing outcome.
Keyphrases
  • cell therapy
  • stem cells
  • wound healing
  • low dose
  • mesenchymal stem cells
  • induced apoptosis
  • bone marrow
  • cell cycle arrest
  • high dose
  • umbilical cord
  • signaling pathway
  • soft tissue
  • oxidative stress
  • cell death