Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study.
Jennifer StimecSaunya DoverEleanor PullenayegumVictor S BlanchetteAndrea S DoriaBrian M FeldmanManuel CarcaoGeorges-Etienne RivardSara J IsraelsAnthony K C ChanMacGregor SteeleStephanie CloutierRobert J KlaassenVictoria E PriceRoona SinhaNicole LaferriereElizabeth ParadisJohn K M WuPaul BabynPublished in: Research and practice in thrombosis and haemostasis (2021)
MRI changes were seen in 39% of subjects. Interval index joint bleeding was associated with an increased risk of later MRI changes, and earlier soft-tissue changes were associated with subsequent osteochondral changes.