Regulatory Effect of JAK2/STAT3 on the Immune Function of Endotoxin-tolerant Dendritic Cells and its Involvement in Acute Liver Failure.
Yukai ChenChaochen HouNaibin YangYanyan YangYouran ChenDeyong KongYuchun JiangMinghao LinSijie ZhengShanshan LiMingqin LuPublished in: Journal of clinical and translational hepatology (2022)
ETDCs alleviated lipopolysaccharide/D-galactosamine-induced ALF by downregulating the JAK2/STAT3 signaling pathway.
Keyphrases
- liver failure
- dendritic cells
- signaling pathway
- hepatitis b virus
- drug induced
- liver injury
- high glucose
- immune response
- diabetic rats
- pi k akt
- inflammatory response
- toll like receptor
- transcription factor
- epithelial mesenchymal transition
- regulatory t cells
- lps induced
- induced apoptosis
- endothelial cells
- oxidative stress
- endoplasmic reticulum stress
- acute respiratory distress syndrome
- respiratory failure