Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors.
Andrew J LeeXin YangJonathan TyrerAleksandra Gentry-MaharajAndy RyanNasim MavaddatAlex P CunninghamTim CarverStephanie ArcherGoska LeslieJatinder KalsiFaiza GabaRanjit ManchandaSimon GaytherSusan J RamusFiona M WalterMarc TischkowitzIan JacobsUsha MenonDouglas F EastonPaul David Peter PharoahAntonis C AntoniouPublished in: Journal of medical genetics (2021)
This multifactorial risk model can facilitate stratification, in particular among women with FH of cancer and/or moderate-risk and high-risk PVs. The model is available via the CanRisk Tool (www.canrisk.org).