In regards to Chu et al.: Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer.
Lukas KäsmannChukwuka EzeJulian TaugnerFarkhad ManapovPublished in: Radiation oncology (London, England) (2020)
We read the article entitled "Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer" with great interest. In that study, the author reported about the importance of PCI timing in limited stage small cell lung cancer (LS-SCLC) in the era of MRI surveillance. In addition, the authors raise the issue of neurotoxicity of PCI. In this letter, we aimed to clarify the value of PCI in LS-SCLC and present ongoing trials regarding PCI and MRI surveillance in SCLC. As a result, we see the need for the development of a prediction tool to estimate the risk of intracranial relapse in LS-SCLC after chemoradiotherapy in order to support shared decision making through improved guidance.
Keyphrases
- percutaneous coronary intervention
- small cell lung cancer
- coronary artery disease
- acute myocardial infarction
- acute coronary syndrome
- antiplatelet therapy
- st elevation myocardial infarction
- st segment elevation myocardial infarction
- atrial fibrillation
- coronary artery bypass grafting
- public health
- magnetic resonance imaging
- white matter
- squamous cell carcinoma
- radiation therapy
- magnetic resonance
- multiple sclerosis
- cerebral ischemia