Heritability of ethanol consumption and pharmacokinetics in a genetically diverse panel of collaborative cross mouse strains and their inbred founders.
Jared R BagleyElissa J CheslerVivek M Philipnull nullJames D JentschPublished in: Alcoholism, clinical and experimental research (2021)
Collectively, this research serves as a foundation for expanded genetic study of ethanol consumption in the CC/DO and related populations. Moreover, we identified reference strains with extreme consumption phenotypes that effectively represent polygenic models of excessive ethanol use.