Topotecan monotherapy for the treatment of relapsed small cell lung cancer in elderly patients: A retrospective analysis.

Hisao ImaiYutaka YamadaHiroyuki MinemuraTomohide SugiyamaMie KotakeKyoichi KairaKenya KanazawaYoichi NakamuraTakashi KasaiYoko ShibataTakayuki KaburagiKoichi Minatonull null

Published in: Thoracic cancer (2018)

Although hematological toxicities (particularly neutropenia) were severe, topotecan showed favorable disease control in both sensitive and refractory patients. Topotecan may thus be a preferred treatment for elderly patients with relapsed SCLC.

Keyphrases

small cell lung cancer
end stage renal disease
acute myeloid leukemia
acute lymphoblastic leukemia
combination therapy
chronic kidney disease
newly diagnosed
multiple myeloma
ejection fraction
hodgkin lymphoma
early onset
middle aged
peritoneal dialysis
open label
study protocol