The combination of kidney function variables with cell cycle arrest biomarkers identifies distinct subphenotypes of sepsis-associated acute kidney injury: a post-hoc analysis (the PHENAKI study).

Dimitri Titeca BeauportMomar DioufDelphine DaubinLy Van VongGuillaume BelliardCédric BruelYoann ZerbibChristophe VinsonneauKada KloucheJulien Maizel

Published in: Renal failure (2024)

Combining conventional kidney function variables with urine measurements of [TIMP-2]*[IGFBP7] might help to identify distinct SA-AKI subphenotypes with different short-term courses and survival rates.

Keyphrases

acute kidney injury
cell cycle arrest
cardiac surgery
cell death
pi k akt
gene expression
signaling pathway