Ranolazine Unveiled: Rediscovering an Old Solution in a New Light.
Giulia Azzurra De SantisTommaso De FerrariFrancesca ParisiMarco FranzinoAgustin Ezequiel MolineroAlessandro Di CarloLorenzo PistelliGiampaolo VettaAntonio ParlavecchioMarco TorreMatteo ParolloGiacomo MansiPietro Paolo TamborrinoAntonio CanuGino GrifoniLuca SegretiAndrea Di CoriStefano Marco VianiGiulio ZucchelliPublished in: Journal of clinical medicine (2024)
Ranolazine is an anti-anginal medication that has demonstrated antiarrhythmic properties by inhibiting both late sodium and potassium currents. Studies have shown promising results for ranolazine in treating both atrial fibrillation and ventricular arrhythmias, particularly when used in combination with other medications. This review explores ranolazine's mechanisms of action and its potential role in cardiac arrhythmias treatment in light of previous clinical studies.