Exopolysaccharide of Enterococcus faecium L15 promotes the osteogenic differentiation of human dental pulp stem cells via p38 MAPK pathway.

Hyewon KimNaeun OhMijin KwonOh-Hee KwonSeockmo KuJeongmin SeoSangho Roh

Published in: Stem cell research & therapy (2022)

The stimulatory effect of L15 extract and EPS on osteogenic differentiation occurred through the p38 MAPK pathway, and L15 EPS enhanced new bone formation in neonate murine calvaria. These data suggest that L15 EPS has therapeutic potential applicable to bone regeneration.

Keyphrases

bone regeneration
stem cells
endothelial cells
mesenchymal stem cells
bone marrow
oxidative stress
electronic health record
big data
biofilm formation
cell therapy
anti inflammatory
machine learning
staphylococcus aureus
artificial intelligence
cystic fibrosis