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Circulating and adipose tissue immune cells in tissue-specific insulin resistance in humans with overweight and obesity.

Inez TrouwborstKristiaan WoutersJohan W JockenKelly M JardonAnouk GijbelsPieter C DagnelieMarleen M J van GreevenbroekCarla J van der KallenCoen D A StehouwerCasper G SchalkwijkNathalie RichardIgor BendikLydia A AfmanEllen E BlaakGijs H Goossens
Published in: Obesity (Silver Spring, Md.) (2023)
The present findings demonstrate that circulating immune cell populations and inflammatory gene expression in aSAT show distinct associations with liver and muscle insulin sensitivity.
Keyphrases
  • gene expression
  • adipose tissue
  • dna methylation
  • skeletal muscle
  • insulin resistance
  • oxidative stress
  • high fat diet
  • metabolic syndrome