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Discovery and validation of circulating miRNAs for the clinical prognosis of severe dengue.

Umaporn LimothaiNattawat JantarangsiNatthasit SuphavejkornkijSasipha TachaboonJanejira DinhuzenWatchadaporn ChaisuriyongSupachoke TrongkamolchaiMananya WanpaisitkulChatchai ChulapornsiriAnongrat TiawilaiThawat TiawilaiTerapong TantawichienUsa ThisyakornNattachai Srisawat
Published in: PLoS neglected tropical diseases (2022)
Our study indicated that circulating miRNAs, especially miR-574-5p and miR-1246, might be a promising diagnostic and prognostic biomarker for severe dengue upon hospital admission, especially when using these biomarkers on days 1 to 2 before the onset of severe dengue complications.
Keyphrases
  • zika virus
  • dengue virus
  • aedes aegypti
  • early onset
  • cell proliferation
  • emergency department
  • long non coding rna
  • healthcare
  • drug induced
  • single cell