Discovery and validation of circulating miRNAs for the clinical prognosis of severe dengue.

Umaporn LimothaiNattawat JantarangsiNatthasit SuphavejkornkijSasipha TachaboonJanejira DinhuzenWatchadaporn ChaisuriyongSupachoke TrongkamolchaiMananya WanpaisitkulChatchai ChulapornsiriAnongrat TiawilaiThawat TiawilaiTerapong TantawichienUsa ThisyakornNattachai Srisawat

Published in: PLoS neglected tropical diseases (2022)

Our study indicated that circulating miRNAs, especially miR-574-5p and miR-1246, might be a promising diagnostic and prognostic biomarker for severe dengue upon hospital admission, especially when using these biomarkers on days 1 to 2 before the onset of severe dengue complications.

Keyphrases

zika virus
dengue virus
aedes aegypti
early onset
cell proliferation
emergency department
long non coding rna
healthcare
drug induced
single cell