Machine-learning-based virtual screening to repurpose drugs for treatment of Candida albicans infection.

Andrew Gao Valentina L Kouznetsova Igor F Tsigelny

Published in: Mycoses (2022)

This study yields promising drugs to be repurposed to combat Candida albicans infection. Future steps include testing the drugs on fungal cells in vitro.

Keyphrases

candida albicans
biofilm formation
machine learning
induced apoptosis
cell cycle arrest
drug induced
cell proliferation
staphylococcus aureus
escherichia coli
cell death
signaling pathway
oxidative stress
endoplasmic reticulum stress