Oxygenated polycyclic aromatic hydrocarbons from ambient particulate matter induce electrophysiological instability in cardiomyocytes.

Sujin JuLeejin LimHan-Yi JiaoSeok ChoiJae Yeoul JunYoung-Jae KiDong-Hyun ChoiJi Yi LeeHeesang Song

Published in: Particle and fibre toxicology (2020)

The concentrations of oxy-PAHs in PM were found to be higher in winter than in summer, which might lead to greater electrophysiological instability through the ROS generation and disruption of calcium regulation.

Keyphrases

polycyclic aromatic hydrocarbons
particulate matter
air pollution
dna damage
cell death
reactive oxygen species
high glucose
endothelial cells