Login / Signup

Glutathione levels and activities of glutathione metabolism enzymes in patients with schizophrenia: A systematic review and meta-analysis.

Sakiko TsugawaYoshihiro NodaRyosuke TarumiYu MimuraKazunari YoshidaYusuke IwataMuhammad ElsalhyMinori KuromiyaShin KuroseFumi MasudaShinji MoritaKamiyu OgyuEric PlitmanMasataka WadaTakahiro MiyazakiAriel Graff-GuerreroMasaru MimuraShinichiro Nakajima
Published in: Journal of psychopharmacology (Oxford, England) (2019)
Our findings suggested that there may be glutathione deficits and abnormalities in the glutathione redox cycle in patients with schizophrenia. However, given the small number of studies examined the entire glutathione system, further studies are needed to elucidate a better understanding of disrupted glutathione function in schizophrenia, which may pave the way for the development of novel therapeutic strategies in this disorder.
Keyphrases
  • traumatic brain injury
  • bipolar disorder
  • case control