Use of fluorescent in-situ hybridisation in salivary gland cytology: A powerful diagnostic tool.
Solène M EvrardJ MeillerouxG DanielC BassetL Lacoste-CollinS VergezE Uro-CosteM Courtade-SaidiPublished in: Cytopathology : official journal of the British Society for Clinical Cytology (2017)
Overall, FISH had a specificity of 100% and a sensitivity of 66.7%. When FISH and cytological analyses were combined, the overall sensitivity was increased to 93.3%. It can thus be concluded that when the FISH analysis is positive, the extent of surgery could be determined with confidence pre-operatively without needing a diagnosis from a frozen section.