2D in-vivo L-COSY spectroscopy identifies neurometabolite alterations in treated multiple sclerosis.

Scott QuadrelliKaren RibbonsJameen ArmOun Al-IedaniJeannette Lechner-ScottRodney LeaSaadallah Ramadan

Published in: Therapeutic advances in neurological disorders (2019)

2D L-COSY has the potential to detect metabolic alterations in the normal-appearing MS brain. Despite examining only a localised region, we could detect metabolic variability associated with symptoms.

Keyphrases

multiple sclerosis
white matter
mass spectrometry
high resolution
ms ms
single molecule
gene expression
human health
blood brain barrier
cerebral ischemia
brain injury
solid state