Engineering an Au nanostar-based liquid phase interfacial ratiometric SERS platform with programmable entropy-driven DNA circuits to detect protein biomarkers in clinical samples.
Guanli FanXiaorong GaoShuling XuXia LiQi ZhangCaifeng DaiQingwang XueHuai-Sheng WangPublished in: Chemical communications (Cambridge, England) (2022)
Developing sensing platforms that simultaneously integrate high sensitivity and accuracy has been a promising but challenging task for the detection of protein biomarkers in clinical samples. Herein, we engineered an Au nanostar-based liquid phase interfacial ratiometric SERS platform with programmable entropy-driven DNA circuits to detect the protein biomarker Mucin 1 (MUC1) in clinical samples.
Keyphrases
- sensitive detection
- ionic liquid
- quantum dots
- gold nanoparticles
- protein protein
- circulating tumor
- single molecule
- cell free
- fluorescent probe
- high throughput
- molecular dynamics simulations
- loop mediated isothermal amplification
- hydrogen peroxide
- binding protein
- living cells
- nitric oxide
- reduced graphene oxide
- raman spectroscopy