Intraoperative Near-Infrared Fluorescence Imaging with Indocyanine Green for Identification of Gastrointestinal Stromal Tumors (GISTs), a Feasibility Study.
Gijsbert M KalisvaartRuben P J MeijerOkker D BijlstraHidde A GalemaWobbe O de SteurHenk H HartgrinkCornelis VerhoefLioe-Fee De Geus-OeiDirk J GrünhagenYvonne M SchrageAlexander L VahrmeijerJos A Van der HagePublished in: Cancers (2022)
GISTs typically show similar fluorescence intensity to the surrounding tissue in NIRF imaging after intraoperative ICG administration. Therefore, intraoperatively administered ICG is currently not applicable for adequate tumor identification, and further research should focus on the development of tumor-specific fluorescent tracers for GISTs.