Intraoperative Near-Infrared Fluorescence Imaging with Indocyanine Green for Identification of Gastrointestinal Stromal Tumors (GISTs), a Feasibility Study.

Gijsbert M KalisvaartRuben P J MeijerOkker D BijlstraHidde A GalemaWobbe O de SteurHenk H HartgrinkCornelis Verhoef Lioe-Fee De Geus-Oei Dirk J van GrünhagenYvonne M SchrageAlexander L VahrmeijerJos van der Hage

Published in: Cancers (2022)

GISTs typically show similar fluorescence intensity to the surrounding tissue in NIRF imaging after intraoperative ICG administration. Therefore, intraoperatively administered ICG is currently not applicable for adequate tumor identification, and further research should focus on the development of tumor-specific fluorescent tracers for GISTs.

Keyphrases

fluorescence imaging
photodynamic therapy
patients undergoing
bioinformatics analysis
high resolution
quantum dots
single molecule