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Population-Based Analysis Of The Use Of Radium-223 For Bone-Metastatic Castration-Resistant Prostate Cancer In Ontario, And Of Factors Associated With Treatment Completion And Outcome.

Sierra ChengVanessa ArcieroHanan GoldbergCamilla TajzlerAileen ManganaroNatascha KozlowskiLeigha RowbottomRachel McDonaldRonald ChowGaurav VasishtSharon ShajiEmily Chu Lee WongMichele PetrovicLiying ZhangCameron PhillipsPawel ZalewskiAnil KapoorNeil E FleshnerEdward ChowUrban Emmenegger
Published in: Cancer management and research (2019)
Despite a lower completion rate than observed under clinical trial conditions, the real-world results achieved with Ra223 are encouraging. If prospectively validated, predictive patient and disease characteristics identified in our cohort might become instrumental to identify mCRPC patients likely to complete and to most benefit from Ra223 therapy.
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