Login / Signup

A review on pulmonary and mediastinal synovial sarcoma.

Kristin Purnama DewiIvana Purnama DewiIswanto IswantoLaksmi Wulandari
Published in: Journal of basic and clinical physiology and pharmacology (2023)
Sarcoma is defined as a tumor located in the thoracic cavity. However, sarcoma can occur on every side of the body. Synovial sarcoma is a rare soft tissue tumor originating from pluripotent with a high malignancy rate. The most common predilection of synovial sarcoma is in the joints. Primary synovial sarcoma of the lung and mediastinum are rare tumors and generally malignant. There are only a few cases have been reported. Definite diagnosis is made by histopathological, immunohistochemistry, and cytogenetic examination. The management strategy for synovial sarcoma requires multimodality treatment with surgery, chemotherapy, and radiotherapy. However, effective and relatively non-toxic therapy for primary synovial sarcoma is still developed. The five years life expectancy is higher if the patient received adjuvant radiotherapy and/or chemotherapy after surgery.
Keyphrases
  • early stage
  • locally advanced
  • radiation therapy
  • minimally invasive
  • soft tissue
  • pulmonary hypertension
  • spinal cord
  • lymph node
  • radiation induced
  • case report
  • atrial fibrillation
  • smoking cessation