Oncostatin M's Involvement in the Pathogenesis of Chronic Rhinosinusitis: Focus on Type 1 and 2 Inflammation.

Chie IshikawaSachio TakenoYukako OkamotoTomohiro KawasumiTakashi KakimotoKota TakemotoManabu NishidaTakashi Ishino Takao HamamotoTsutomu UedaAkio Tanaka

Published in: Biomedicines (2023)

OSM is involved in the pathogenesis of CRS in both type 1 and type 2 inflammation, suggesting the OSM signaling pathway as a potential therapeutic target for modulating epithelial stromal interactions.

Keyphrases

signaling pathway
oxidative stress
chronic rhinosinusitis
pi k akt
epithelial mesenchymal transition
cell proliferation
induced apoptosis
risk assessment
endoplasmic reticulum stress