Chemotaxonomy and cytotoxicity of the liverwort Porella Viridissima.
Benjamin MétoyerNicolas LebouvierEdouard HnawiaLouis ThouvenotFengrui WangLiva Harinantenaina RakotondraibePhila RaharivelomananaYoshinori AsakawaMohammed NourPublished in: Natural product research (2019)
The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis. Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer.