Therapeutic potentialities of green tea (Camellia sinensis) in ischemic stroke: biochemical and molecular evidence.
Shakiba AzamiFatemeh ForouzanfarPublished in: Metabolic brain disease (2023)
Ischemic stroke is a leading cause of disability and death in patients. Despite considerable recent advances in the treatment of ischemic stroke, only a limited number of effective neuroprotective agents are available for stroke. Green tea (Camellia sinensis) is a popular herbal plant, and numerous studies have indicated its health benefits for several diseases. Green tea is of interest due to its high content of catechin derivatives, including epicatechin, gallocatechin, epicatechin gallate, epigallocatechin, and epigallocatechin-3-gallate. This review tried to develop a feasible background for the potential effects of green tea and its bioactive derivatives concerning protection against ischemic stroke. Green tea's antioxidants, anti-inflammatory, anti-apoptotic, and neuroprotective effects are believed to be efficacious in stroke treatment. Evidence supports the idea that green tea can be used to assist in treating ischemic stroke. Green tea has a protective effect against ischemic stroke; Epigallocatechin-3-gallate: EGCG, Epicatechin: EC, Gallocatechin gallate: GCG, Epigallocatechin: EGC, Epicatechin gallate: ECG, Catechin: C, Gallocatechin: GC.
Keyphrases
- atrial fibrillation
- anti inflammatory
- end stage renal disease
- healthcare
- chronic kidney disease
- public health
- multiple sclerosis
- mental health
- newly diagnosed
- ejection fraction
- cell death
- peritoneal dialysis
- mass spectrometry
- combination therapy
- blood pressure
- risk assessment
- human health
- replacement therapy
- patient reported outcomes
- subarachnoid hemorrhage
- liquid chromatography
- gas chromatography
- case control