Neuroimaging and epigenetic analysis reveal novel epigenetic loci in major depressive disorder.

Hyun-Ho YangKyu-Man HanAram KimYoubin KangWoo-Suk TaeMi-Ryung HanByung-Joo Ham

Published in: Psychological medicine (2024)

Through combining DNA methylation and neuroimaging analyses, negative correlations were identified between the cortical thickness of the left VLPFC and DNA methylation levels of eight DMPs. Our findings could improve our understanding of the pathophysiology of MDD.

Keyphrases

dna methylation
major depressive disorder
genome wide
bipolar disorder
gene expression
copy number
optical coherence tomography
single cell
genome wide association
data analysis