Haptoglobin Phenotype and Intensive Glycemic Control for Coronary Artery Disease Risk Reduction in People With Type 2 Diabetes: The ADVANCE Study.
Leah E CahillRachel A WarrenAllie S CarewAndrew P LevyJohn SappMichelle SamuelElizabeth SelvinSamantha K LavalléeNeil PoulterMichel MarreStephen HarrapGiuseppe ManciaKatie HarrisJohn ChalmersMark WoodwardEric B RimmPublished in: Diabetes care (2024)
Our findings suggest that intensive glycemic control contributes to the prevention of major CAD events among ADVANCE participants with the Hp2-2 phenotype and no previous CVD and are in alignment with our hypothesis that intensive glycemic control may be beneficial in a subset of people with the Hp2-2 phenotype.