Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion.
Chan-Hyuk LeeSang Hak YiByoung-Soo ShinHyun Goo KangPublished in: Diagnostics (Basel, Switzerland) (2022)
Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.
Keyphrases
- middle cerebral artery
- cerebral ischemia
- internal carotid artery
- atrial fibrillation
- subarachnoid hemorrhage
- liver failure
- ischemia reperfusion injury
- blood brain barrier
- acute myocardial infarction
- brain injury
- respiratory failure
- high dose
- drug induced
- left atrial
- direct oral anticoagulants
- catheter ablation
- aortic dissection
- percutaneous coronary intervention
- acute coronary syndrome
- oxidative stress
- acute respiratory distress syndrome
- endovascular treatment