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Age-related brain deviations and aggression.

Nathalie E HolzDorothea L FlorisAlberto LleraPascal M AggensteinerSeyed Mostafa KiaThomas WolfersSarah BaumeisterBoris BöttingerJeffrey C GlennonPieter J HoekstraAndrea DietrichMelanie C SaamUlrike M E SchulzeDavid J LythgoeSteve C R WilliamsParamala SantoshMireia Rosa-JusticiaNuria BargalloJosefina Castro-FornielesCelso ArangoMaria J PenzolSusanne WalitzaAndreas Meyer-LindenbergMarcel ZwiersBarbara FrankeJan BuitelaarJilly NaaijenDaniel BrandeisChristian BeckmannTobias BanaschewskiAndre F Marquand
Published in: Psychological medicine (2022)
Overall increased age-related deviations in the amygdala in DBD suggest a maturational delay, which has to be further validated in future studies. Further, the integration of individual deviation patterns from multiple imaging modalities allowed to dissect some of the heterogeneity of DBD and identified the DMN, the striatum and the amygdala as neural signatures that were associated with aggression.
Keyphrases
  • resting state
  • functional connectivity
  • prefrontal cortex
  • high resolution
  • single cell
  • temporal lobe epilepsy
  • current status
  • white matter
  • case control
  • stress induced
  • gene expression
  • multiple sclerosis
  • brain injury