HIV drug resistance among adults initiating antiretroviral therapy in Uganda.

Christine WateraDeogratius SsemwangaGrace NamayanjaJuliet AsioTom LutaloAlice NamaleGrace SanyuIsaac SsewanyanaJesus Fidel Gonzalez-SalazarJamirah NazziwaMaria NanyonjoElliot J RaizesUsher KabugaChristina MwangiWilford KirungiJoshua MusinguziKaggwa MugaggaEdward Katongole MbiddePontiano Kaleebu

Published in: The Journal of antimicrobial chemotherapy (2021)

We observed a high HIVDR prevalence for NNRTIs among adults prior to initiating or reinitiating ART in Uganda. This is above WHO's recommended threshold of 10% when countries should consider changing from NNRTI- to dolutegravir-based first-line regimens. This recommendation was adopted in the revised Ugandan ART guidelines. Dolutegravir-containing ART regimens are preferred for first- and second-line ART regimens.

Keyphrases

antiretroviral therapy
hiv infected
human immunodeficiency virus
hiv positive
hiv infected patients
hiv aids
risk factors