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Impairment of Proteasome Function in Podocytes Leads to CKD.

Shin-Ichi MakinoNaritoshi ShirataJuan Alejandro Oliva TrejoKanae Yamamoto-NonakaHiroyuki YamadaTakafumi MiyakeKiyoshi MoriTakahiko NakagawaYoshitaka TashiroHirofumi YamashitaEiichiro UchinoRyosuke TakahashiKatsuhiko Asanuma
Published in: Journal of the American Society of Nephrology : JASN (2021)
Impairment of proteasome function in podocytes led to CKD, and antioxidants and autophagy activators can be therapeutic agents for age-dependent CKD.
Keyphrases
  • chronic kidney disease
  • high glucose
  • cell death
  • diabetic nephropathy
  • signaling pathway