Survival of dogs with pituitary-dependent hyperadrenocorticism treated twice daily with low doses of trilostane.

Paula García San JoséCarolina Arenas BermejoDaniel Alonso-MiguelSandra González SanzIrene Clares MoralMiriam Portero FuentesMaría Dolores Pérez-Alenza

Published in: The Veterinary record (2022)

Low-dose trilostane treatment twice daily provides slightly longer survival than previously reported for dogs with PDH treated once or twice daily at higher doses. Older age, presence of calcinosis cutis, low BCS and higher platelet count, but not systemic hypertension, are predictive of poorer prognosis in dogs with PDH.

Keyphrases

physical activity
low dose
blood pressure
free survival
high dose
peripheral blood
community dwelling
growth hormone
drug induced