Impact of Varicocele on Testicular Oxidative Stress and Sperm Parameters in Experimental Animals: A Systematic Review and Meta-Analysis.

Giorgio Ivan Russo Ramadan Saleh Federica Finocchi Almas Ramadhani Juma Damayanthi Durairajanayagam Oguzhan Kahraman Emrullah Sogutdelen Ioannis Sokolakis Ranjit B Vishwakarma Fahmi Bahar Ahmed M Harraz Parviz K Kavoussi Widi Atmoko Eric Chung Naveen Kumar Wael Zohdy Amarnath Rambhatla Mohamed Arafa Nguyen Ho Vinh Phuoc Gianmaria Salvio Aldo Eugenio Calogero Tuncay Toprak Germar-Michael Pinggera Rossella Cannarella Giovanni M Colpi Forum Taha Abo-Almagd Abdel-Meguid Hamoda Rupin Shah Ashok Agarwal

Published in: The world journal of men's health (2024)

This SRMA indicates a significant increase in levels of testicular MDA and SDF and a reduction of sperm quality in experimental animals with varicocele. These findings support the potential role of testicular OS in the development of varicocele-induced testicular damage.

Keyphrases

germ cell
oxidative stress
diabetic rats
dna damage
high glucose
breast cancer cells
risk assessment
ischemia reperfusion injury
cell proliferation
induced apoptosis