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Bispecific Antibody Molecule Inhibits Tumor Cell Proliferation More Efficiently Than the Two-Molecule Combination.

Anna-Luisa VolkAman MebrahtuBong-Kook KoMagnus LundqvistMaximilian KarlanderHyun-Jong LeeFredrik Y FrejdKyu-Tae KimJong-Seo LeeJohan Rockberg
Published in: Drugs in R&D (2021)
Our study shows that transcriptome analysis can be used to validate the choice of receptor targets and guide the design of novel multi-specific molecules. The inherent modularity of the AffiMab format renders it readily applicable to other receptor targets.
Keyphrases
  • cell proliferation
  • binding protein
  • signaling pathway