Urine metabolomic biomarkers for prediction of isolated fetal congenital heart defect.

Perry FriedmanAli YilmazZafer UgurFaryal JafarAmy WhittenIlyas UstunOnur Turkoglu Stewart Francis GrahamRay Bahado Singh

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

We report a novel, noninvasive approach, based on the analysis of maternal urine for isolated CHD detection. Further, the dysregulation of lipid- and folate metabolism appears to support prior data on the mechanism of CHD.

Keyphrases

electronic health record
loop mediated isothermal amplification
birth weight
real time pcr
label free
pregnant women
machine learning
data analysis
gestational age
weight loss