PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells.

Anna Mallol Maria Guirola Bernhard Payer

Published in: Epigenetics & chromatin (2019)

In summary, here we provide new insight and spatiotemporal resolution to the progression and regulation of epigenome remodeling along mouse PGC migration in vivo and link epigenetic reprogramming to its developmental context.

Keyphrases

dna methylation
induced apoptosis
gene expression
cell cycle arrest
genome wide
skeletal muscle
copy number
single molecule
endoplasmic reticulum stress
oxidative stress
signaling pathway
pi k akt